mRNA Hello Greeting Card

Transcriptional control is the regulation of gene expression through a combination of transcription factors, RNA polymerase, and specific DNA elements known as promoters, enhancers, silencers, and locus-control elements. This process results in the production of pre-mRNA, which undergoes processing to become a functional mRNA. This includes splicing out introns, adding a 5' cap and a 3' poly(A) tail, and potentially editing the mRNA sequence. The final mRNA molecule in eukaryotes has three parts: a 5' untranslated region (5' UTR), a coding region with triplet codons encoding amino acids, and a 3' untranslated region (3' UTR).

The rapid authorization of two mRNA-based COVID-19 vaccines just 11 months after the discovery of the virus highlights the potential of mRNA technology. So far, most mRNA applications have focused on vaccines for infectious diseases and cancer, which can be effective with low doses and local delivery due to the innate immune-stimulating properties of some mRNA. There has also been progress in mRNA-based protein or cell immunotherapies, which pose different manufacturing and formulation challenges as they require high protein expression in target cells and tissues and may need to be administered repeatedly. Over the past few years, there has been clinical progress in COVID-19 vaccines, Omicron boosters, and vaccines for seasonal flu, Epstein-Barr virus, HIV, and cancer.

"mRNA Hello" is the newest way to send your greetings that's shaking up the science community. The message is written in the language of genetics, so not only will you be putting a smile on your friend's face, but also making their inner biology nerd do a happy dance. Whether you're saying "Hi" to your best bud or "Welcome" to a new co-worker, "mRNA Hello" is the perfect way to put a creative spin on your greetings. This unique card is guaranteed to make a lasting impression and show that you're not afraid to think outside the box (or nucleus, in this case). So, next time you want to send your hellos in a witty way, let "mRNA Hello" do the talking.

• Material: 14.77 oz/yd² (350 g/m²) paperboard
• Size: 5″ × 7″ (127 × 178 mm)
• Vibrant colors
• Comes with a complimentary envelope